Stochastic model of yeast cell-cycle network
نویسندگان
چکیده
منابع مشابه
Stochastic Model of Yeast Cell Cycle Network
Biological functions in living cells are controlled by protein interaction and genetic networks. These molecular networks should be dynamically stable against various fluctuations which are inevitable in the living world. In this paper, we propose and study a stochastic model for the network regulating the cell cycle of the budding yeast. The stochasticity in the model is controlled by a temper...
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This paper presents the definition, solution and validation of a stochastic model of the budding yeast cell cycle, based on Stochastic Petri Nets (SPN). A specific family of SPNs is selected for building a stochastic version of a well-established deterministic model. We describe the procedure followed in defining the SPN model from the deterministic ODE model, a procedure that can be largely au...
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We use the recently proposed Nested Stochastic Simulation Algorithm (Nested SSA) to simulate the cell cycle model for budding yeast. The results show that Nested SSA is able to significantly reduce the computational cost while capturing the essential dynamical features of the system. AMS subject classifications: 65C05, 60G17, 74A25, 92C42
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ژورنال
عنوان ژورنال: Physica D: Nonlinear Phenomena
سال: 2006
ISSN: 0167-2789
DOI: 10.1016/j.physd.2006.05.009